Oral Peptide Delivery and the Intestinal Barrier Problem
Gastric acid and intestinal enzymes destroy most peptides before they reach absorptive cells.
Elias Kowalski
Section
3 stories in Drug Delivery Beyond Injections.
Gastric acid and intestinal enzymes destroy most peptides before they reach absorptive cells.
The area postrema bypasses the blood-brain barrier to trigger nausea in roughly half of GLP-1 users.
Most GLP-1 patients quit within a year, often before the drug delivers visible results.