Dual GLP-1 GIP Receptor Agonists Compared
Tirzepatide's biased signaling may preserve receptor sensitivity better than standard agonists.
Sofia Ashworth
Section
GLP-1 Science and Mechanisms
8 stories in GLP-1 Science and Mechanisms.
GIP Mechanism of Action in Weight Loss
GIP's weight-loss mechanism spans pancreas, brain, and adipose tissue thermogenesis.
Naomi Osei
DPP-4 Degradation of GLP-1 and Half-Life Engineering
Engineering amino acid swaps and albumin binding stretch GLP-1's survival from minutes to a week.
Dara Chen
GLP-1 Physiology Beyond the Pancreas
GLP-1 receptors throughout the body create effects far beyond blood sugar control.
Estelle Ibrahim
GLP-1 and GIP Combined Mechanism of Action
The two hormones work in opposing directions to stabilize blood sugar.
Vera Ashworth
Molecular Structure of GLP-1 Receptor Agonists
Why DPP-4 enzyme destruction forced all GLP-1 drug designs.
Julian Bennett
GLP-1 Signaling Pathway in Metabolic Regulation
cAMP amplification explains why GLP-1 drugs pose minimal hypoglycemia risk.
Elias Mbeki
GLP-1 Receptors in the Brain
GLP-1 receptors throughout the brain may protect against addiction and cognitive decline.
Nico Bergström