Approved Intranasal CNS Drugs and Their Delivery Mechanisms
How esketamine, naloxone and nalmefene use the nose to bypass the blood-brain barrier.
Tobias Wrenfield
Section
Nose-to-Brain (N2B) Delivery
6 stories in Nose-to-Brain (N2B) Delivery.
Nasal Epithelium Barriers to CNS Drug Delivery
Mucus, tight junctions, and anatomy stand between a nasal spray and the brain.
Priya Subramaniam
Nose-to-Brain Delivery in Neurodegenerative Disease Research
Intranasal delivery bypasses the blood-brain barrier using direct nerve pathways to the brain.
Mei-Lin Tso
Nose-to-Brain Delivery for Large-Molecule Biologics
Nanoparticles enable large biologics to reach the brain through the nasal cavity.
Tobias Wrenfield
Nose-to-Brain Drug Delivery Pathway Explained
Human imaging confirmed insulin reaches the brain via nasal delivery within thirty minutes.
Mei-Lin Tso
Olfactory Pathway Anatomy and Drug Transport Mechanisms
Distinguishing two nose-to-brain routes reveals how anatomical design shapes drug targeting.
Tobias Wrenfield