Nanoparticle and Peptide Therapeutics
Drug Delivery Nanoparticle Platform Types Compared
Each nanoparticle platform trades different advantages in reaching target tissues.
Priya Subramaniam
· 12 min read
glpletter — Page 4
The Latest
Nose-to-Brain (N2B) Delivery
Approved Intranasal CNS Drugs and Their Delivery Mechanisms
How esketamine, naloxone and nalmefene use the nose to bypass the blood-brain barrier.
Tobias Wrenfield
Nose-to-Brain (N2B) Delivery
Nasal Epithelium Barriers to CNS Drug Delivery
Mucus, tight junctions, and anatomy stand between a nasal spray and the brain.
Priya Subramaniam
Nose-to-Brain (N2B) Delivery
Nose-to-Brain Delivery in Neurodegenerative Disease Research
Intranasal delivery bypasses the blood-brain barrier using direct nerve pathways to the brain.
Mei-Lin Tso
Nose-to-Brain (N2B) Delivery
Nose-to-Brain Delivery for Large-Molecule Biologics
Nanoparticles enable large biologics to reach the brain through the nasal cavity.
Tobias Wrenfield
GLP-1 Side Effects and Patient Experience
GLP-1 Side Effect Profile and Treatment Discontinuation Rates
Most GLP-1 patients quit within a year, driven by nausea and cost barriers.
Mei-Lin Tso
GLP-1 Side Effects and Patient Experience
Gastroparesis Risk With GLP-1 Agonist Use
Delayed gastric emptying is common with GLP-1 drugs; true gastroparesis is rare.
Amara Osei-Bonsu
GLP-1 Side Effects and Patient Experience
GLP-1 Skin and Hypersensitivity Reactions
Dermatologists miss GLP-1 side effects because skin receptors weren't on their radar.
Amara Osei-Bonsu
GLP-1 Side Effects and Patient Experience
GLP-1 Side Effects After Stopping Treatment
What happens to your body when you stop taking GLP-1s.
Amara Osei-Bonsu
GLP-1 Side Effects and Patient Experience
GLP-1 Gastrointestinal Mechanisms Behind Nausea and Diarrhea
Scientists trace GLP-1 nausea to a toxin-detection system in the brainstem.
Amara Osei-Bonsu
GLP-1 Side Effects and Patient Experience
GLP-1 Injection Site Reactions and Subcutaneous Tissue Effects
Depot formation under the skin, not manufacturing flaws, causes these reactions.
Amara Osei-Bonsu
GLP-1 Side Effects and Patient Experience
Duration and Resolution of GLP-1 Nausea and Vomiting
Most patients who quit GLP-1 therapy abandon it just before their nausea would naturally resolve.
Amara Osei-Bonsu