FeaturesHow the Lungs Absorb Peptides and Where That Breaks Down for GLP-1s
Degradation and poor permeability make the lungs a dead end for GLP-1 drugs.
Mei-Lin Tso·
Nanoparticle and Peptide TherapeuticsGLP-1 Receptor Agonists as Neurological Pipeline Candidates Enabled by Nose-to-Brain Nanoparticle Access
Intranasal nanoparticles could deliver GLP-1 drugs to brain targets for neurological disease.
Mei-Lin Tso·
Drug Delivery Beyond InjectionsIntranasal GLP-1 Delivery as the Clinical Bridge for Needle-Averse Patients Who Fail Oral Semaglutide
A needle-free nasal spray could reach patients' brains where pills and injections both fail.
Mei-Lin Tso·
Nanoparticle and Peptide TherapeuticsIntellectual Property Strategy for Nanoparticle Drug Delivery Platforms
Platform patents multiply value by stacking composition, method, and application claims together.
Mei-Lin Tso·
Nanoparticle and Peptide TherapeuticsMucosal Absorption Barriers for Peptide Biologics
Enzymatic barriers and tight junctions make nasal delivery far harder than injection for peptides.
Mei-Lin Tso·
Nanoparticle and Peptide TherapeuticsCompanies Developing Intranasal Routes for GLP-1 and Metabolic Peptide Delivery
Nasal delivery could ease GLP-1 side effects while boosting brain concentrations.
Mei-Lin Tso·
Nanoparticle and Peptide TherapeuticsNanoparticle Drug Delivery Systems in Approved Therapies
Approved nanoparticles solve specific delivery failures free drugs cannot overcome.
Mei-Lin Tso·
Nanoparticle and Peptide TherapeuticsDrugs That Can Cross the Blood-Brain Barrier
Researchers race to unlock delivery methods as barrier blocks ninety-eight percent of brain drugs.
Mei-Lin Tso·
Nose-to-Brain (N2B) DeliveryNose-to-Brain Delivery in Neurodegenerative Disease Research
Intranasal delivery bypasses the blood-brain barrier via cranial nerves.
Mei-Lin Tso·
GLP-1 Side Effects and Patient ExperienceGLP-1 Side Effect Profile and Treatment Discontinuation Rates
Many patients abandon GLP-1 drugs despite trial success rates.
Mei-Lin Tso·
Drug Delivery Beyond InjectionsTransdermal Peptide Delivery Research and Current Limits
Skin's molecular gatekeeping makes most peptide drugs impossible to deliver without injections.
Mei-Lin Tso·
Drug Delivery Beyond InjectionsNeedle Aversion and Injection Anxiety in Chronic Disease Management
Fear of needles keeps many chronic disease patients from taking life-saving injected medications.
Mei-Lin Tso·